Xbrane Biopharma

Xbrane's main aim is to achieve a positive cash flow as soon as possible and as previously announced, by no later than Q1 2025. Therefore, Xbrane’s board has decided to focus the development portfolio on biosimilar candidates with established commercialization partners: Ximluci® (Lucentis® biosimilar), BIIB801 (Cimzia® biosimilar candidate), and Xdivane™ (Opdivo® biosimilar candidate) with the ambition of out-licensing the latter in the near future. Xdarzane™ (Darzalex® biosimilar candidate) is being maintained in the portfolio while the development of Xtrudane™ (Keytruda® biosimilar candidate) has been terminated.

Because of the focused development portfolio, and the in-house process development for BIIB801 and Xdivane™ is being finalized, Xbrane is implementing a cost-savings scheme expected to generate cost savings of around SEK 50 million annually when fully implemented. The savings take place in all areas and include staff reductions totaling about 40 positions, including both permanent staff and consultants. The savings are realized gradually and are expected to be fully implemented in Q3 2024.

"Our business and purpose is based on driving a change towards a sustainable healthcare system with equal opportunity for health globally. To be able to drive this long-term change, we must now focus on our short-term financial sustainability. The focus of our development portfolio and the implementation of this cost-saving scheme are unfortunately necessary measures to achieve this. I deeply regret that our team will be affected, and that valuable expertise must leave the company." says Martin Åmark, CEO of Xbrane.

Xbrane's long-term strategic ambition to become a leading biosimilar developer remains. The company has identified several development opportunities for biosimilars potential launch in 2030–2035. It is Xbrane's plan and ambition to begin developing an expanded portfolio as soon as judged possible.