IRLAB Therapeutics

The research will be presented by IRLABs, Erik Werner, PhD, Senior Data Scientist at IRLAB, at StanCon 2026 – the International Conference on Bayesian Inference and Probabilistic Programming – on August 17–21, 2026, in Uppsala. The conference brings together world-leading statisticians and is a recognized forum for advanced statistical analysis.

The analysis is based on pooled data from IRLAB’s randomized, placebo-controlled phase IIa and phase IIb studies of mesdopetam. The research team, led by Dr. Werner, has constructed and analyzed a large number of Bayesian statistical models. Although the numerical estimates may vary, the conclusion is unequivocal: The analysis confirms mesdopetam's favorable effect profile and its anti-dyskinetic efficacyacross a broad range of statistical models.

“It is encouraging that mesdopetam’s effect on levodopa-induced dyskinesia can be confirmed in this extensive analysis based on two phase II studies and a large number of statistical models. The result is valuable for the project in the preparations for the next step in the clinical development program and strengthens our position in the ongoing discussions with potential partners,” says Nicholas Waters, Executive Vice President & Head of R&D, IRLAB Therapeutics.

Mesdopetam is a dopamine D3 receptor antagonist in clinical development for the treatment of levodopa-induced dyskinesia (LID) – a common and difficult-to-treat condition in Parkinson’s disease. The analysis to be presented at StanCon 2026 builds on a Bayesian meta-analysis that was presented at the International Congress of the International Parkinson and Movement Disorder Society in 2024.