AlzeCure Pharma
AlzeCure gets presentation accepted on disease-modifying effects of ACD856 at Alzheimer’s conference
AlzeCure Pharma AB (publ) (FN STO: ALZCUR), a pharmaceutical company that develops a broad portfolio of small molecule candidate drugs for diseases affecting the central nervous system, with projects in both Alzheimer’s disease and pain, today announced that an abstract with preclinical data on NeuroRestore ACD856 demonstrating its potential disease-modifying effects has been accepted for presentation at the annual Alzheimer's conference CTAD, Clinical Trials in Alzheimer's Disease, which this year is being held in Boston on October 24-27.
The abstract, titled NeuroRestore ACD856, a Trk-PAM in clinical development for Alzheimer’s disease shows neuroprotective and neurorestorative effects, will be presented at the international Alzheimer conference CTAD 2023 by Martin Jönsson, CEO at AlzeCure. Other authors are Pontus Forsell, Veronica Lidell, Azita Rasti, Gunnar Nordvall and Johan Sandin.
The presentation includes new preclinical results with ACD856, the lead candidate drug within the NeuroRestore platform. The data show that the substance exhibits both protective and regenerative effects on nerve cells, indicating potentially disease-modifying properties of this class of molecules.
”Among other things, our new data shows that ACD856 protects nerve cells against the toxic effects of the protein amyloid-beta, which is the main component of the harmful amyloid plaques that form in the brains of Alzheimer's patients", said Pontus Forsell, Head of Discovery & Research at AlzeCure Pharma AB.
Previous preclinical studies have shown that AlzeCure's drug candidates strengthen communication between nerve cells and improve cognitive ability, including learning and memory functions. ACD856 has undergone phase I clinical studies, where both good safety and tolerability were demonstrated in humans, but also that the candidate drug crossed the blood-brain barrier and that the substance activated parts of the brain that are central to both cognition and depression treatment.
“We are very pleased to have the opportunity to present our new data at such a large and recognized Alzheimer's conference as CTAD. With the positive clinical results we previously obtained with ACD856, as well as these new preclinical results that further support a disease-modifying and protective effect, we have both a very promising and unique candidate drug in our research portfolio, in an area of great unmet medical need", said Martin Jönsson, CEO of AlzeCure Pharma AB.
The abstract and the poster will be available on AlzeCure's website after the presentation (https://www.alzecurepharma.se/sv/presentationer-och-intervjuer).
Datum | 2023-09-26, kl 10:00 |
Källa | MFN |
AlzeCure gets presentation accepted on disease-modifying effects of ACD856 at Alzheimer’s conference | |
Martin Jönsson CEO And Pontus Forsell Head Of Discovery And Research AlzeCure Pharma 2023 |
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